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Investigation into Acute Hepatitis of Unknown Aetiology in Children in England

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United kingdom Health Security Agency (UKHSA). Investigation into acute hepatitis of unknown aetiology in children in England. Technical briefing 3. 19 May 2022.

The UK Health Security Agency (UKHSA) is working with the National Health Service (NHS) and the public health agencies of the 4 nations of the United Kingdom (UK) to investigate the potential cause of an unusually high number of acute hepatitis cases being seen in children in the past few weeks. There is no known association with travel, and hepatitis viruses (A to E) have not been detected in these children.

Unless otherwise stated this technical briefing uses data cut-off of 16 May 2022 to allow time for analyses. More recent case numbers may be cited in other UKHSA public updates but are not included in the analyses presented here. The 4 UK nations are conducting a coordinated investigation and data continues to be reconciled across the UK. For this reason, summary epidemiology data is presented for all 4 nations, whilst some detailed analyses can only be presented for single countries at present.

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