Low Detection Rate of Bordetella pertussis Using the BioFire FilmArray …

Guillot S, Mizrahi A, Armatys N, et al. Low Detection Rate of Bordetella pertussis Using the BioFire FilmArray Respiratory Panel 2plus. Open Forum Infect Dis. 2020;7(8):ofaa267. Published 2020 Jul 2. doi:10.1093/ofid/ofaa267

Syndromic respiratory panels are increasingly used worldwide. Their performance for detection of Bordetella pertussis needs to be evaluated. We found that the FilmArray Respiratory Panel 2plus (RP2+) assay, which uses the pertussis toxin promoter target for B. pertussis, can only detect highly charged samples. Negative RP2+ results should not be interpreted as an absence of B. pertussis in clinical samples.

Keywords
Bordetella pertussis; FilmArray respiratory panel; molecular diagnosis; whooping cough.

Disponível Em: <https://pubmed.ncbi.nlm.nih.gov/>