Guidelines on Transfusion for Fetuses, Neonates and Older Children.

New HV, Berryman J, Bolton-Maggs PH, Cantwell C, Chalmers EA, Davies T, Gottstein R, Kelleher A, Kumar S, Morley SL, Stanworth SJ; British Committee for Standards in Haematology. Guidelines on transfusion for fetuses, neonates and older children. Br J Haematol. 2016 Dec;175(5):784-828. doi: 10.1111/bjh.14233. Epub 2016 Nov 11. PubMed PMID: 27861734.

The guideline is a revision of the 2004 British Committee for Standards in Haematology (BCSH) guideline on transfusion in neonates and older children (BCSH, 2004). Although there has been little evidence on which to base paediatric clinical transfusion decisions in the past, there have been a number of studies and national audits published over recent years that contribute to decision‐making in this area. In addition there have been changes to other guidance, including the management of neonatal jaundice National Institute for Health and Clinical Excellence (NICE, 2010) and the requirement for cytomegalovirus (CMV) seronegative components.

The clinical section focuses largely on aspects relating to transfusion indications and administration, whereas the laboratory section contains most of the information relating to pre‐transfusion testing and component selection. Details relating to blood component specification and typical transfusion volumes and rates may be found in Appendix 1.

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