PICS Statement: Increased Number of Reported Cases of Novel Presentation of Multisystem …

United Kingdom. Paediatric Intensive Care Society. PICS Statement: Increased number of reported cases of novel presentation of multisystem inflammatory disease. 27 April 2020

Over the weekend, PICS members received an email alert from NHS England highlighting a small rise in the number of cases of critically ill children presenting with an unusualclinical picture. Many of these children had tested positive for COVID-19, while some had not. The alert indicated“the cases have in common overlapping features of toxic shock syndrome and atypical Kawasaki disease with blood parameters consistent with severe COVID-19 in children. Abdominal pain and gastrointestinal symptoms have been a common feature as has cardiac inflammation”.

It is important to highlight that,both in the UK and inother countries,there have still been very few cases of critically unwell children with COVID-19 admitted to paediatric intensive care units. However, an early case report relating to COVID-19 presenting as Kawasaki syndrome has been published recently [1], and PICS isaware of a small number of children nationally who appear to fit the clinical picture described in the NHS England alert.

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